From wound management to surgical incisions and beyond…
Fidia cares.

The leader in hyaluronic acid science
Grounded in long-term research and worldwide clinical use, Fidia’s hyaluronic acid expertise supports skin and wound care innovation.1
60+
Years of research &
development in
Hyaluronic acid
1,200+
Patents on
Hyaluronic acid
310+
Clinical studies on
Hyaluronic Acid
120+
Countries where
Fidia is present
Our products

Hyalo4® Care Hydrogels
Rx only, hyaluronic acid-based hydrogels indicated for the dressing and management of wounds, post-incision care, first- and second-degree burns, and skin irritations. They’re intended to provide a soothing, moist environment and protect skin and wounds from abrasion, friction, and desiccation.2,3
KEY BENEFITS2,3
- Contains hyaluronic acid (0.2%) to support natural wound healing
- Prescription-based hydrogels provide a soothing, moist environment at the wound/incision area
- Protects against abrasions, frictions, and desiccation of the skin
- Designed for topical use as a part of standard wound care and/or skin care protocols
KEY Ingredient2,3
Hyalastine® (sodium hyaluronate salt, 0.2%)
Intended For2,3
Partial- to full-thickness dermal ulcers (pressure sores, venous stasis ulcers, arterial ulcers, diabetic ulcers), cuts, abrasions, donor sites, post-operative incisions, skin irritations, and first- and second-degree burns.
Settings for Use
Clinical and professional care settings, including wound care, dermatologic, surgical, urgent care, and supervised home/outpatient care environments.
Available Sizes
100g tube, white hydrogel or clear hydrogel
Coming Soon: 30g tube, white hydrogel or clear hydrogel
Resources

COL-FID4 Care™ Collagen Dressing
A sterile, Rx only, single-use wound dressing composed of native 100% bovine Type 1 collagen. When applied to the wound surface, it absorbs exudate and helps maintain a moist environment to aid in the management of wound healing.4
KEY BENEFITS2,3
- Composed of 100% native bovine Type 1 collagen
- Absorbs wound exudate at the wound surface
- Helps maintain a moist wound environment for wound management
- Dressing changes should be performed within 7 days, depending on amount of drainage and exudate
- Intended for short-term use up to 4 weeks. For long-term use, an assessment by a healthcare practitioner is recommended.
KEY Ingredient2,3
100% Native Bovine Type 1 Collagen
Intended For2,3
Partial- and full-thickness wounds, including pressure ulcers (Stage I-IV), venous stasis and diabetic ulcers, ulcers of mixed vascular etiology, cuts, and abrasions.
Settings for Use
Professional wound care settings, including wound clinics, podiatry, dermatology, vascular care practices involved in ulcer management and other supervised home/outpatient care environments.
Available Sizes
2″x2″ dressings, 5 per box
Coming Soon: 4”×5” dressing, 1 per box
Resources
SETTINGS FOR CLINICAL USE

Wound care specialists & podiatrists
For partial- to-full-thickness wounds, including acute and chronic ulcers, Hyalo4® Care may support the healing process.2,3 COL-FID4 Care™ is ideal in situations where exudate management is of high priority, along with maintaining moisture balance.4

Dermatologists & Cosmetic Surgeons
For surgical incisions, burns and skin irritations. Hyalo4® Care Hydrogels provide a moist environment where protection against friction, abrasion, and desiccation is important.2,3 For dermatologists who also manage dermal ulcers, COL-FID4 Care™ may be of interest.4

Plastic & Reconstructive Surgeons
For post-surgical wound management, Hyalo4® Care Hydrogels support incisions, donor sites, and post-procedural skin irritations where moisture control are priorities.2,3 Works with standard of care and healthcare provider
recommendations focused on maintaining appropriate moisture conditions to support the healing process.

Home Care Clinics & Urgent Care Centers
Hyalo4® Care Hydrogels are well-suited for care environments that manage bed sores, cuts, abrasions, first-and-second degree burns, venous stasis, diabetic ulcers and more.2,3 With COL-FID4 Care™, HCPs can extend dressing changes (no more than 7 days)4 based on their professional evaluation, offering flexibility when planning follow-up protocols.
References:
- Data on file at Fidia Farmaceutici S.p.A., Abano Terme (PD) Italy
- Hyalo4® Care Hydrogel Package Insert. Fidia Farmaceutici S.p.A. Abano Terme, Italy; 2022
- Hyalo4® Care Clear Hydrogel Package Insert. Fidia Farmaceutici S.p.A. Abano Terme, Italy; 2022
- COL-FID4 Care™ Package Insert. Fidia Farmaceutici S.p.A. Abano Terme, Italy; 2025

Explore our U.S. Professional websites
© 2026 FIDIA PHARMA USA INC., Florham Park, NJ 07932, a wholly owned subsidiary of Fidia Farmaceutici S.p.A.
HYALO4® CARE AND COL-FID4 CARE™ are trademarks of Fidia Farmaceutici S.p.A., Abano Terme (PD) Italy
To report an adverse event or a product complaint, call Fidia Pharma USA Inc. at 866-749-2542.
FID1159-06.2026 June 2026
For more information, visit our website www.fidiapharma.us
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The information on this website is provided for educational purposes only and is not intended to provide medical advice to healthcare providers or replace a discussion with your doctor as outlined in our terms of use. It is advised that you discuss your treatment options with your doctor before making any decisions.
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Fidia Pharma USA Inc.
100 Campus Drive, Suite 105, Florham Park, NJ 07932, USA
Phone Number: +1 866-749-2542